PROtective Ventilation with a low versus high Inspiratory Oxygen fraction (PROVIO) and its effects on postoperative pulmonary complications: protocol for a randomized controlled trial

Table 2 Intraoperative ventilation settings for the PROVIO trial

	Low-FiO₂ group	High-FiO₂ group
FiO₂	0.30	0.80
V_T	8 ml/kg	8 ml/kg
PEEP	6–8 cmH₂O	6–8 cmH₂O
I:E	1:2	1:2
RR	Adjusted according to E_TCO₂ (35–45 mmHg)	Adjusted according to E_TCO₂ (35–45 mmHg)
P_max	30 cmH₂O	30 cmH₂O

E_TCO₂ end-tidal carbon dioxide, FiO₂ inspiratory oxygen fraction, I:R Inspiratory to Expiratory ratio, PEEP positive end-expiratory pressure, P_max maximum peak airway pressure, RR respiratory rate, V_T tidal volume

ISSN: 1745-6215