Fig. 1

Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT). Information about the selection, recruitment and evaluations carried out in each period. Abbreviations: 6MWT six-minute walk test, BMI body mass index, CG control group, ESS Epworth Sleepiness Scale, FFQ food frequency questionnaire, PSQI Pittsburgh Sleep Quality Index, IWQOL-LITE questionnaire on the Impact of Weight on Quality of Life-lite, WG water group