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Fig. 2 | Trials

Fig. 2

From: A randomised controlled trial evaluating arrhythmia burden, risk of sudden cardiac death and stroke in patients with Fabry disease: the role of implantable loop recorders (RaILRoAD) compared with current standard practice

Fig. 2

Block randomisation process. The high-risk features include LVH (MWT > 12 mm or elevated LVMi greater than two SD), LA dilatation (M-mode measurement > 40 mm or biplane volume > 34 mL on echo), elevated troponin (above centre specific reference ranges), prolonged QRS duration > 120 ms, presence of LGE on CMR imaging, a MSSI greater than 20. *There will be a variable number of patients from each high-risk feature group to ensure a variable risk profile within the study cohort (zero risk factors – 20 participants, one risk factor – 40 participants, two risk factors – 40 participants, three risk factors – 40 participants, four or five risk factors – 24 participants. Abbreviations: CMR cardiac magnetic resonance imaging, ECG electrocardiogram, ILR implantable loop recorder, LA left atrium, LGE late gadolinium enhancement, LVH left ventricular hypertrophy, LVMi indexed left ventricular mass, MSSI Mainz severity score index; MWT maximum wall thickness, SD standard deviation, TTE transthoracic echocardiography.

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Trials

ISSN: 1745-6215