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Table 3 Sample size calculations for the primary comparisons in the study 1

From: Nifurtimox versus benznidazole or placebo for asymptomatic Trypanosoma cruzi infection (Equivalence of Usual Interventions for Trypanosomiasis - EQUITY): study protocol for a randomised controlled trial

  1. 1. Needed for each comparison group, based on assumptions of trypanocidal effect explained in the text, including 5% of participant losses
  2. 2. Cells with no shade imply feasible scenarios with 60 participants for each group, the recruitment goal for Colombia. Light grey cells imply the need to have 60–80 participants per group to make this comparison viable. Dark grey cells imply the need to have more than 80 participants per group
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Trials

ISSN: 1745-6215