Arthritis prevention in the pre-clinical phase of RA with abatacept (the APIPPRA study): a multi-centre, randomised, double-blind, parallel-group, placebo-controlled clinical trial protocol

Table 2 Schedule of blood and urine sampling

Biological Sample	Type & No.	Tube Cap Colour	Baseline	Weeks 13	Weeks 26	Weeks 39	Weeks 52	Weeks 65	Weeks 78	Weeks 91	Weeks 104
Serum	SST x 2	Red	18ml^a	18ml	18ml	18ml	18ml	18ml	18ml	18ml	18ml
PBMC	Heparin x 5	Green	40ml	40ml	40ml	40ml	40ml	40ml	40ml	40ml	40ml
RNA	Tempus x 2	Blue	5ml	5ml	5ml	5ml	5ml	5ml	5ml	5ml	5ml
DNA	EDTA x 1	Purple	7ml
Routine drug monitoring^b	According to local procedures			10ml	10ml	10ml	10ml	10ml	10ml	10ml	10ml
Urine	Plain x 1	Beige	20ml	20ml	20ml	20ml	20ml	20ml	20ml	20ml	20ml
Total volume of blood draw			70ml	73ml	73ml	73ml	73ml	73ml	73ml	73ml	73ml

ISSN: 1745-6215