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Table 1 Macronutrient composition and bioactive factors in bovine and human colostrum, term and preterm milk

From: FortiColos – a multicentre study using bovine colostrum as a fortifier to human milk in very preterm infants: study protocol for a randomised controlled pilot trial

 

Bovine colostrum

Human colostrum

Preterm human colostrum

Term bovine milk

Term human milk

Preterm human milk

Protein, g/L

60–135a

11–32c

19f

34c

9–12g

12.7f

 Casein, g/L

26b

3.0–5.6c

 

2~30c

4–4.8g

 

 Whey, g/L

35–119a

4.3–11.1c

 

4~50c

6–7.2g

 

 α-Lactalbumin, g/L

2.04c

2.56c

 

1–1.5c

2–3c

 

 β-Lactoglobulin, g/L

14.3c

Nonec

 

3–4c

Nonec

 

 Lactoferrin, g/L

1.0–2.0c

5.0–7.0c

 

0.01–0.1c

1.0–2.0c

 

 Immunoglobulins, g/L

20–150c

1.14–20c

 

0.6–1.0c

1.2c

 

 Lactoperoxidase, mg/L

11–45c

5.17c

 

13–30c

5.17c

 

 Osteopontin, mg/L

Not determinedc

1493.4c

 

18c

138c

 

 Lysozyme, mg/L

0.14–0.7c

270–430c

 

0.07–0.6c

160–460c

 

 Superoxide dismutase, U/mL

0.06–2.88c

18.7–22.5c

 

0.06–2.88c

11.2c

 

 Platelet-activating factor-acetylhydroxylase, μg/L

Nonec

0.95–1.19c

 

Nonec

1.16–1.21c

 

 Alkaline phosphatase, μkat/L

6.84h

1.79c

 

4.49c

0.92c

 

 Transforming growth factor-β, μg/L

150–1150c

1366c

 

13–71c

953c

 

 Insulin-like growth-I, μg/L

49–2000c

29–49c

 

4–150c

3–6c

 

 Insulin-like growth-II, μg/L

400–600c

10.5c

 

50–100c

35c

 

 Epidermal growth factor, μg/L

4–324.2c

35–438c

 

2–155c

20–111c

 

Lactose, g/L

18.9–32a

44–59d

57–74f

49a

67–78g

73f

Fat, g/L

50–80a

20–29e

26f

37a

32–3g

35f

  1. aAbd El-Fattah AM [32], bKorhonen HJ [33], cChatterton DEW [34], dEspinosa-Martos I [35], eJensen RG [36], fBoyce C [37], gBallard O [38], hZanker IA [39]