Effect of home-based transcranial direct current stimulation (tDCS) on cognitive function in patients with mild cognitive impairment: a study protocol for a randomized, double-blind, cross-over study

Table 1 List of tests conducted at each visit

Phase	Screening	Treatment I	Washout	Treatment II	Follow-up
Day	0	1	14	28	42	56
Visit	S1	T1	T2	T3	T4	F1
Visual recognition task		O	O	O	O	O
Neuropsychological test^a		O	O	O	O	O
Basal symptom and sign	O	O	O	O	O	O
Vital sign^b	O	O	O	O	O	O
MMSE-DS/GDS/CGI^c/CGS/S-IADL/K-GDS	O	O	O	O	O	O
Questionnaire^d		O	O	O	O	O
Concomitant medication check	O	O	O	O	O	O
Adverse event check		O	O	O	O	O

^aNeuropsychological tests: CERAD, letter number sequencing, spatial span
^bSitting systolic/diastolic blood pressure, pulse, and temperature were measured
^cCGI: not measured at screening
^dQuestionnaires for investigator, subject, and guardian were administered for efficacy assessment
For investigator: MARDRS/HAMD/HAMA
For subject: STAI/PSQI/Hand Function Rating Scale
For guardian: NPI

ISSN: 1745-6215