Update on the General Practice Optimising Structured Monitoring to Improve Clinical Outcomes in Type 2 Diabetes (GP-OSMOTIC) trial: statistical analysis plan for a multi-centre randomised controlled trial

Table 6 Estimated glycated haemoglobin (HbA1c) and between-group differences by history of severe hypoglycaemia and personalised HbA1c target for intervention and control groups (sub-group analyses)

	Estimated mean HbA1c (95% CI)		Difference in estimated mean HbA1c and HbA1c target		Unadjusted		Adjusted^a
	Intervention group (n=)	Control group (n=)	Intervention group (n=)	Control group (n=)	Intervention vs. control between-group differences (95% CI)	P value	Intervention vs. control between-group differences (95% CI)	P value
Severe hypoglycaemia
History of severe hypoglycaemia^b
Baseline
6 months
12 months
No history of severe hypoglycaemia^c
Baseline
6 months
12 months
Personalised HbA1c target
Personalised target^d
Baseline
6 months
12 months
No personalised target^e
Baseline
6 months
12 months

ISSN: 1745-6215