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Table 3 Data recorded during the study period

From: Enteral Nutrition Tolerance And REspiratory Support (ENTARES) Study in preterm infants: study protocol for a randomized controlled trial

Ventilation/respiration parametersa

– Respiratory support technique

– PEEP/CPAP (cmH2O)

– Peak inspiratory pressure (PIP, cmH2O)

– Flow (L/min)

– FiO2 (%)

– Respiratory rate (acts/min)

– Transcutaneous O2 blood saturation (SatO2 TC %)

– Capillary/arterial blood gas test

– Episodes of apnea (> 20 s or > 5 s if followed by bradycardia/desaturation), bradycardia (Heart rate ≤ 80 bpm) and desaturation (SatO2 TC ≤ 80%)/day

– Silverman score

Feeding parametersb

– Parenteral nutrition intake (mL/kg/day)

– Enteral nutrition intake (mL/kg/day)

– Total caloric intake (Kcal/kg/day)

– Type of milk: human milk or formula

– Modality of feeding (bolus, gavage, continuous feeding)

– Modality of fortification (if any; type of fortifier: standard, target, or adjustable fortification)

– Enteral feeding interruptions (episodes/day)

– Not given feeds (episodes/day)

– Pathologic gastric residual volumes (episodes/day)

– Vomits and/or regurgitations (episodes/day)

– Abdominal distention (medium score/day)

Auxological parametersc

– Weight (g)

– Length (cm)

– Cranial circumference (cm)

Overall health status parametersd

– Patent ductus arteriosus

– Intraventricular hemorrhage

– Leukomalacia

– Retinopathy of prematurity

– Pneumothorax

– Blood transfusion

– NEC

– Intestinal perforation

  1. aVentilation/respiration parameters will be recorded at enrollment, at achievement of half enteral feeding and full enteral feeding, at the beginning of oral feeding, at achievement of full oral feeding, and at any change in respiratory assistance strategy. Apnea monitoring will extend until any respiratory support is needed (except for O2 supplementation per nasal cannula)
  2. bFeeding parameters will be recorded daily until full enteral feeding is achieved, at the beginning of oral feeding, at achievement of full oral feeding, and at any change in respiratory assistance strategy
  3. cAuxological parameters will be recorded at the time of enrollment, upon achieving half enteral feeding and full enteral feeding, and at discharge
  4. dRelevant clinical events/diagnosis will be recorded from enrollment until discharge