From: Outcomes, Interventions and Funding in Randomised Research Published in High-Impact Journals
All journals | General journals | Specialty journals | P * | |
---|---|---|---|---|
Trials (n) Interventions (n) | 360 416 | 210 249 | 150 167 | |
Intervention | ||||
Drug | 233 (56%) | 120 (48%) | 113 (68%) | < 0.0001 |
Device | 17 (4%) | 9 (4%) | 8 (5%) | |
Procedure | 49 (12%) | 29 (12%) | 20 (12%) | |
Other | 117 (28%) | 91 (37%) | 26 (16%) | |
Primary outcome | ||||
Single | 237 (66%) | 135 (64%) | 102 (68%) | 0.006 |
Co-primary | 47 (13%) | 37 (18%) | 10 (7%) | |
Composite | 76 (21%) | 38 (18%) | 38 (25%) | |
Surrogate | 223 (62%) | 131 (62%) | 92 (61%) | 0.90 |
Mixed | 50 (14%) | 30 (14%) | 20 (13%) | |
Hard | 87 (24%) | 49 (23%) | 38 (25%) | |
Clearly stated in abstract | 286 (79%) | 179 (85%) | 107 (71%) | 0.002 |
Funding | ||||
Any industry | 136 (38%) | 53 (25%) | 83 (55%) | < 0.001 |
Non-industry | 220 (61%) | 156 (74%) | 64 (43%) | |
Not stated | 4 (1%) | 1 (< 1%) | 3 (2%) |