Table 1 Study drug administration
Up to 30 mins pre KTS | + 2 h post KTS | + 10 h post KTS | + 18 h post KTS | + 26 h post KTS | |
|---|---|---|---|---|---|
Intervention group 1 Normal creatinine <120 μmol/L | 1 g TXA IV | 1 g TXA oral | 1 g TXA oral | 1 g TXA oral | 1 g TXA oral |
Intervention group 1 High (A) creatinine level 120–249 μmol/L | 0.5 g TXA IV | 0.5 g TXA oral | 0.5 g TXA oral | 0.5 g TXA oral | 0.5 g TXA oral |
Intervention group 1 High (B) creatinine level 250–499 μmol/L | 0.5 g TXA IV | – | 0.5 g TXA oral | – | 0.5 g TXA oral |
Intervention group 1 High (C) creatinine level ≥ 500 μmol/L | 0.5 g TXA IV | – | – | – | 0.5 g TXA oral |
Intervention group 2 Normal creatinine level < 120 μmol/L | 1 g TXA IV | – | – | – | – |
Intervention group 2 High (A) creatinine level 120–249 μmol/L | 0.5 g TXA IV | – | – | – | – |
Intervention group 2 High (B) creatinine level 250–499 μmol/L | 0.5 g TXA IV | – | – | – | – |
Intervention group 2 High (C) creatinine level ≥ 500 μmol/L | 0.5 g TXA IV | – | – | – | – |
Control group 3 – no TXA All creatinine levels | – | – | – | – | – |