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Table 1 Nutritional protocol for the control and intervention trial arms

From: Combined Protocol for Acute Malnutrition Study (ComPAS) in rural South Sudan and urban Kenya: study protocol for a randomized controlled trial

 

Standard protocol (control)

Combined protocol (intervention)

Admission criteria

OTP

• MUAC <125 mm

and/or

• Bilateral pitting oedema (+/++)

and

• Clinically uncomplicateda

• WHZ <−3

and/or

• MUAC <115 mm

and/or

• Bilateral pitting oedema (+/++)

and

• Clinically uncomplicateda

SFP

• Discharged from OTP

and/or

• WHZ <−2 to >−3

and/or

• MUAC 115 to <125 mm

and

• Clinically uncomplicateda

Treatment frequency

OTP

MUAC <115 mm and/or oedema (+/++)

Weekly

SFP

MUAC 115 to <125 mm

14 days

Treatment transition criteria

▪ Child meets OTP ‘cured’ definition as described below

• Two consecutive MUAC measurements at or above 115 mm

and

• No oedema

Dosage

OTP

MUAC <115 mm and/or oedema (+/++)

RUTF 200 kcal/kg/day

RUTF 1000 kcal/day (2 sachets/day)

SFP

MUAC 115 to <125 mm

RUSF 500 kcal/day (1 sachet/day)

RUTF 500 kcal/day (1 sachet/day)

Cured

OTP

≥125 mm for 2 consecutive measurements and no oedema

▪ Child maintains MUAC ≥115 mm for 2 consecutive visitsb

and/or

▪ WHZ >−3 for 2 consecutive visitsb

and

▪ No oedema for 2 consecutive visits

SFP

Child maintains WHZ >−2 and/or MUAC ≥125 mm for a period of 2 consecutive visitsb

  1. aClinically uncomplicated: passes the appetite test, no Integrated Management of Childhood Illness (IMCI) danger signs [11]/no serious medical complications
  2. bDependent on which criteria the child was admitted on