From: Financial management of large, multi-center trials in a challenging funding milieu
• Encourage multi-disciplinary teamwork that engages the Principal Investigator, Coordinating Center, Research Administration at the prime, subaward institutions, and the funding agency. | |
• Allocate resources based on results, not just effort. | |
• Maintain open-mindedness and flexibility when addressing sites’ concerns. | |
• Provide Core support and sufficient resources for study start-up. | |
• Accept that sites will be discontinued and sites will be added. | |
• Project that recruitment will take longer and the outcome event rate may be lower than predicted. | |
• Reinforce the model’s principles to site staff. |