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Fig. 2 | Trials

Fig. 2

From: Financial management of large, multi-center trials in a challenging funding milieu

Fig. 2

Comparison of the hybrid model used by D2d vs. a cost reimbursement subaward agreement for clinical sites. The cost reimbursement model includes the originally submitted budgets for sites (as cost reimbursement agreements) and actual expenses for non-site components (Coordinating Center, drug distribution, central lab) through the end of the recruitment phase without any budget reductions for underperformance. The hybrid model used by D2d includes actual spending (clinical sites and non-site components) through the end of the recruitment phase

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