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Table 3 Quality of studies included

From: N-of-1 trials in the clinical care of patients in developing countries: a systematic review

Author (date)

Sources of risk of bias

Selection bias

(random sequence generation)

Selection bias

(allocation concealment)

Reporting bias

(incomplete outcome data)

Reporting bias

(selective reporting)

Performance bias

(blinding of participants and clinicians)

Inadequate cycles

(risk of error – especially type 2)

Appropriateness of treatment for design

Appropriate washout period

Huang, et al., (2014) [32]

Lowa

Low

Low

Low

Low

Low

Unclear

Low

Yuhong, et al.,(2012) [33]

Low

Low

Low

Low

Unclear

Low

Unclear

High

Wang et al., (2010) [35]

Low

Low

Low

Low

Low

Low

Unclear

High

Yu, et al., (2012) [36]

Low

Unclear

Low

Low

High

Low

Unclear

High

Zhang, et al., (2012) [37]

Low

Unclear

Low

Low

High

Low

Unclear

High

Louly, et al., (2009) [34]

Low

Low

Low

Low

Low

Low

Low

Low

  1. aLevel of risk