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Fig. 1 | Trials

Fig. 1

From: Efficacy of high-intensity, low-volume interval training compared to continuous aerobic training on insulin resistance, skeletal muscle structure and function in adults with metabolic syndrome: study protocol for a randomized controlled clinical trial (Intraining-MET)

Fig. 1

General design of the study, schedule of enrollment, intervention and assessment*. a After signing the informed consent, the patients will undergo medical and biochemical evaluation. Once inclusion/exclusion criteria are verified, recruited patients will be evaluated for muscle mass, fiber type composition of the vastus lateralis muscle (VLM), and cardio-respiratory physical capacity. Then, patients will be assigned to a high-intensity/low-volume interval training (HIIT-low volume) or continuous aerobic exercise training (CAE) intervention. A final reevaluation will be performed. b Evaluations during both enrollment and close out periods are expected to last 2 weeks. The intervention will last 12 weeks. HOMA-IR, Homeostatic Model Assessment-Insulin Resistance; HbA1c, glycated hemoglobin; IR, insulin resistance; MS, metabolic syndrome

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