Fig. 2

Schedule of enrolment, interventions, and assessments according to SPIRIT [36]. ENROL, enrolment; EQ-5D-5 L, Euro-QoL five health dimensions questionnaire; INT, interventions; MIPD, minimally invasive pancreatoduodenectomy; OPD, open pancreatoduodenectomy; QLQ-C30, Quality of life questionnaire including 30 questions; d, day(s); w, weeks; m, months; postop, postoperative. * Includes histopathology. ^ Includes primary study endpoint and are all prospectively registered up to 6 months postoperatively