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Table 6 Regression models for supplementary analysis

From: Efficacy of pre-operative quadriceps strength training on knee-extensor strength before and shortly following total knee arthroplasty: protocol for a randomized, dose-response trial (The QUADX-1 trial)

Supplementary analyses (primary outcome at primary endpoint)

 

Dependent variable (y)

Independent variable (x)

Linear regression model

Change in isometric knee-extensor strength Δt0-t1

Exercise adherence

 Seconds of total time-under-tension (TUT)

 Number of completed exercise sessions

Supplementary analyses (secondary outcomes at primary and secondary endpoints)

Linear regression models

Change in isometric knee-extensor strength Δt0-t2, Δt0-t3

Exercise adherence

 Seconds of total time-under-tension (TUT)

 Number of completed exercise sessions

Change in 6-minute walk test for distance (6MWT) Δt0-t1, t0-t2, t0-t3

Change in stair climb test (SCT) Δt0-t1, t0-t2, t0-t3

Change in Knee Osteoarthritis Outcome Score (KOOS) subscales Δ t0-t1, t0-t3

Change in Oxford Knee Score (OKS) Δ t0-t1, t0-t3

Change in current knee pain (Numeric Rating Scale, NRS) Δ t0-t1, t0-t2, t0-t3

Change in knee pain during the last week (Numeric Rating Scale, NRS) Δ t0-t1, t0-t3

Need for surgery (yes/don’t know/no)

Averse events