Table 4 Outcomes for primary and secondary analyses
| Â | t0 Baseline | t1 After 12-week exercise | t2 After surgery at hospital discharge | t3 3Â months after surgery | Between-group contrasts (change scores) 95% CI (p) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean, SD | Gp. 2 | Gp. 4 | Gp. 6 | Gp. 2 | Gp. 4 | Gp. 6 | Gp. 2 | Gp. 4 | Gp. 6 | Gp. 2 | Gp. 4 | Gp. 6 | Â |
Isometric knee-extensor strength (Nm/kg) |  |  |  |  |  |  |  |  |  |  |  |  | Primary analysis Δt0-t1 Secondary analysis Δt0- t2, t0-t3 |
6-Minute Walking Test for distance (6MWT) |  |  |  |  |  |  |  |  |  |  |  |  | Secondary analysis Δt0-t1, Δt0-t2, Δt0-t3 |
Stair Climb Test (SCT) |  |  |  |  |  |  |  |  |  |  |  |  | Secondary analysis Δt0-t1, Δt0-t2, Δt0-t3 |
Knee Osteoarthritis Outcome Score (KOOS) |  |  |  |  |  |  | Na | Na | Na |  |  |  | Secondary analysis Δt0-t1, Δt0-t3 |
Oxford Knee Score (OKS) |  |  |  |  |  |  | Na | Na | Na |  |  |  | Secondary analysis Δt0-t1, Δt0-t3 |
Current knee pain (Numeric Rating Scale (NRS) 0–10) |  |  |  |  |  |  |  |  |  |  |  |  | Secondary analysis Δt0-t1, Δt0-t2, Δt0-t3 |
Knee pain during the last week (NRS 0–10) |  |  |  |  |  |  | Na | Na | Na |  |  |  | Secondary analysis Δt0-t1, Δt0-t3 |
Need for surgery now (yes/don’t know/no) | Na | Na | Na |  |  |  | Na | Na | Na | Na | Na | Na | Secondary analysis |
Exercise adherence | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 • No. sessions (prescribed, completed, % completed) | Na | Na | Na |  |  |  |  |  |  | Na | Na | Na | Secondary analysis |
 • Seconds of total time-under-tension (TUT) (prescribed, completed, % completed) | Na | Na | Na |  |  |  |  |  |  | Na | Na | Na | Secondary analysis |
Adverse events | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Secondary analysis |