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Fig. 3 | Trials

Fig. 3

From: Effects of four antiplatelet/statin combined strategies on immune and inflammatory responses in patients with acute myocardial infarction undergoing pharmacoinvasive strategy: Design and rationale of the B and T Types of Lymphocytes Evaluation in Acute Myocardial Infarction (BATTLE-AMI) study: study protocol for a randomized controlled trial

Fig. 3

The BATTLE-AMI study flowchart. After fibrinolytic therapy performed in the 6 h after onset of symptoms, subjects with STEMI will be referred to the hospital for coronary angiography and PCI, if necessary. Those patients admitted to the hospital within 24 h of STEMI will be randomized to one of the four assignments in a 1:1:1:1 ratio (ticagrelor/rosuvastatin, ticagrelor/simvastatin plus ezetimibe, clopidogrel/rosuvastatin, or clopidogrel/simvastatin plus ezetimibe). Blood, urine, and feces samples will be collected at baseline, 30 days, and 180 days for metabolomics, proteomics, microbiota, and flow-cytometry studies. cMRI studies will be performed during peri-hospitalization period and at 30 and 180 days

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