Table 4 Level of Trial Steering Committee (TSC) and Data Management Committee (DMC) reporting split by journal
Committee(s) reported | Journal (N in cohort) | Total (N = 264) | |||
|---|---|---|---|---|---|
BMJ (N = 16) | NEJM (N = 55) | Lancet (N = 66) | HTA (N = 127) | ||
TSC and DMC reported | 4 25.0% | 31 56.4% | 19 28.8% | 55 43.3% | 109 41.3% |
N papers reporting TSC (N papers reporting DMC) | |||||
Acknowledged/listed | 2 (2) | 19 (23) | 14 (15) | 52 (50) | 87 (90) |
Main paper | 2 (2) | 7 (6) | 5 (4) | 3 (5) | 17 (17) |
Supplementary paper | 0 (0) | 0 (0) | 0 (0) | NA | 0 (0) |
Protocol | 0 (0) | 5 (2) | 0 (0) | NA | 5 (2) |
TSC only reported | 2 12.5% | 3 5.5% | 1 1.5% | 29 22.8% | 35 13.3% |
N papers reporting TSC | |||||
Acknowledged/listed | 1 | 2 | 1 | 19 | 23 |
Main paper | 1 | 1 | 0 | 10 | 12 |
Supplementary paper | 0 | 0 | 0 | NA | 0 |
Protocol | 0 | 0 | 0 | NA | 0 |
Reason for no DMC provided | 0 | 0 | 0 | 3 | 3 |
DMC only reported | 0 0.0% | 17 30.9% | 26 39.4 | 6 4.7% | 49 18.6% |
N papers reporting DMC | |||||
Acknowledged / listed | 0 | 8 | 3 | 5 | 16 |
Main paper | 0 | 6 | 22 | 1 | 29 |
Supplementary paper | 0 | 1 | 1 | NA | 2 |
Protocol | 0 | 2 | 0 | NA | 2 |
Reason for no TSC provided | 0 | 0 | 0 | 0 | 0 |
Neither committee reported | 10 62.5% | 4 7.3% | 20 30.3% | 37 29.1% | 71 26.9% |
N papers | |||||
Reason for no TSC provided | 0 | 0 | 0 | 0 | 0 |
Reason for no DMC provided | 0 | 2 | 0 | 0 | 2 |