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Table 3 Results for pediatric appendicitis study

From: Estimating relative risks in multicenter studies with a small number of centers — which methods to use? A simulation study

Model

RR

95% CI or CrI

GLM-Bin

0.76

0.51–1.11

GEE binomial

0.79

0.56–1.13

GEE binomial, KC-corrected

 

0.53–1.19

GEE Poisson

0.80

0.56–1.14

GEE Poisson, KC-corrected

 

0.53–1.21

GLMM binomial

0.76

0.51–1.11

GLMM binomial bootstrap

 

0.51–1.10

Bayesian binomial GLMM

0.73

0.49–1.07

  1. Abbreviations: CrI Credible interval, GEE Generalized estimating equation, GLM-Bin Log-binomial regression model, GLMM Generalized linear mixed model, KC Kauermann and Carroll, RR Relative risk
  2. The KC bias correction in the GEE models adjusts the robust SE for the small number of centers (estimate of RR does not change)
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Trials

ISSN: 1745-6215