Skip to main content

Table 2 Panel of biomarkers

From: Effects of a liquefied petroleum gas stove intervention on pollutant exposure and adult cardiopulmonary outcomes (CHAP): study protocol for a randomized controlled trial

Biomarker Purpose Matrix Method
Intercellular adhesion molecule 1 (ICAM-1) Endothelial marker of cardiovascular function DBS Immunoassay
Vascular cellular adhesion molecule 1 (VCAM-1) Endothelial marker of cardiovascular function DBS Immunoassay
Endothelin-1 Endothelial marker of cardiovascular function DBS Immunoassay
E-selectin Endothelial marker of cardiovascular function DBS Immunoassay
C-reactive protein (CRP) Inflammation marker DBS Immunoassay
Interleukin-6 (IL-6) Inflammation marker DBS Immunoassay
von Willebrand factor antigen (vWF)a Blood coagulation protein DBS Immunoassay
Hemoglobin A1C (HbA1C) Marker of glycemic control DBS Spectrophotometry
Hemoglobin (Hb) Clinical biomarker DBS Spectrophotometry
Lipidsa Clinical biomarkers DBS Immunoassay
P53 tumor-associated antigen antibodies (p53 TAA antibodies)a Lung and other cancer biomarker DBS Array assay
F2-isoprostanes Inflammation markers DBS Immunoassay
Clara cell protein (CC16) Lung insult marker DBS Immunoassay
8OH-deoxyguanosine (8OHdG) Oxidative stress marker Urine LC-MS/MS
Myeloperoxidase (MPO)a Oxidative stress marker DBS Immunoassay
Cytochrome P450 (Cyp450)a Enzyme induction DBS Immunoassay
4-OH cotinine Short term tobacco smoke biomarker Urine LC-MS/MS
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL)a Tobacco smoke biomarker   
Polycyclic aromatic hydrocarbons (1-OH pyrene and 1-, and 2-naphthols) Carcinogen exposure biomarker Urine GC-MS/MS
Volatile organic chemicals (mercapturate metabolites)a Carcinogen exposure biomarker Urine LC-MS/MS
  1. aSubject to sample volume availability