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Table 1 Magnetic resonance imaging tumour regression grade (mrTRG)

From: A rectal cancer feasibility study with an embedded phase III trial design assessing magnetic resonance tumour regression grade (mrTRG) as a novel biomarker to stratify management by good and poor response to chemoradiotherapy (TRIGGER): study protocol for a randomised controlled trial

mrTRG 1 – Complete radiological response (linear scar only)
mrTRG 2 – Good response (dense fibrosis, no obvious tumour signal)
mrTRG 3 – Moderate response (>50% fibrosis and visible intermediate signal)
mrTRG 4 – Slight response (mostly tumour)
mrTRG 5 – No response/regrowth of tumour