Table 2 Description of core area outlined in OMERACT Filter 2.0 [33,34,35]
From: Creation of a core outcome set for clinical trials of people with shoulder pain: a study protocol
Core Area | Description |
|---|---|
Death | Includes possible specifications of death, such as generic or disease-specific (all-cause versus disease-specific mortality), and intervention-specific (for example, death due to surgery) |
Life impact | Can include domains such as activity and participation and domains within the concept of health-related quality of life such as functional status, general health perceptions, and overall quality of life |
Resource use/economic impact | Economic impact of health conditions on both society and the individual |
Pathophysiological manifestations | This core area is meant to assess whether or not the effect of the intervention specifically targets the pathophysiology of the health condition and may include psychosocial manifestations. Example domains include: body function, reversible manifestations (including modifiable risk factors and actual manifestations of ill health), and irreversible manifestations (including non-modifiable risk factors and damage). This can also include biomarkers and surrogate outcomes |