Investigating the effect of independent, blinded digital image assessment on the STOP GAP trial

Table 4 Speed of healing over 6 weeks by assessment method

Lesion size assessment method	Treatment group	Number in group	Mean (SD) speed of healing (cm²/day)	Difference in means (ciclosporin –prednisolone)	Adjusted difference^a (95% CI)	p value	p value^b
Trial measurements	Ciclosporin	57	−0.21 (1.00)	−0.074	0.003 (−0.20 to 0.21)	0.97	1.00
Trial measurements	Prednisolone	51	−0.14 (0.42)	−0.074	0.003 (−0.20 to 0.21)	0.97
Unblinded measurements only	Ciclosporin	57	−0.21 (1.00)	−0.035	0.003 (−0.24 to 0.25)	0.98
Unblinded measurements only	Prednisolone	51	−0.18 (0.47)	−0.035	0.003 (−0.24 to 0.25)	0.98

^aAdjusted by stratification factors baseline lesion size and presence of underlying systemic disease
^b p value for test of homogeneity

ISSN: 1745-6215