Table 2 Agreement between unblinded measurements and trial measurements
From: Investigating the effect of independent, blinded digital image assessment on the STOP GAP trial
Ciclosporin (n = 57) | Prednisolone (n = 51) | Total (n = 108) | |
|---|---|---|---|
Lesion size at baseline (cm2) | |||
Mean difference [SD] | 4.9 [10.2] | 6.7 [22.1] | 5.8 [16.8] |
Mean absolute difference [SD] | 5.5 [9.9] | 7.0 [22.0] | 6.2 [16.7] |
ICC (95% CI) | 0.97 (0.94 to 0.99) | 0.84 (0.73 to 0.91) | 0.92 (0.88 to 0.95) |
Lesion size at 6 weeks (cm2) | |||
Mean difference [SD] | 4.7 [12.4] | 5.2 [25.4] | 4.9 [19.5] |
Mean absolute difference [SD] | 4.8 [12.3] | 5.3 [25.3] | 5.0 [19.5] |
ICC (95% CI) | 0.92 (0.85 to 0.95) | 0.76 (0.61 to 0.85) | 0.83 (0.76 to 0.88) |
Speed of healing (cm2/day) | |||
Mean difference [SD] | 0.00 [0.24] | −0.04 [0.20] | −0.02 [0.22] |
Mean absolute difference [SD] | 0.10 [0.21] | 0.09 [0.19] | 0.10 [0.20] |
ICC (95% CI) | 0.97 (0.95 to 0.98) | 0.89 (0.82 to 0.94) | 0.96 (0.94 to 0.97) |