Abelmoschus manihot – a traditional Chinese medicine versus losartan potassium for treating IgA nephropathy: study protocol for a randomized controlled trial

Table 1 Study visits

Item	Screening visit	V1	V2	V3	V4	V5	V6
Visit	Screening visit	V1	V2	V3	V4	V5	V6
Time	−1w	0w ± 7d	4w ± 7d	12w ± 7d	24w ± 7d	36w ± 7d	48w ± 7d
Confirm eligibility	√	√
Written informed consent	√
Clinical and demographic information	√	√
Physical examination	√	√	√	√	√	√	√
Signs and symptoms	√	√	√	√	√	√	√
24-h urinary proteinuria	√	√	√	√	√	√	√
24-h urine creatinine	√	√	√	√	√	√	√
Routine urine test	√	√	√	√	√	√	√
Urine pregnancy test		√
Routine blood test		√	√	√	√	√	√
Blood biochemical tests		√	√	√	√	√	√
eGFR	√	√	√	√	√	√	√
Serum cystatin C and high-sensitivity C-reactive protein		√			√		√
Electrocardiogram and		√					√
Chest X-ray examinations		√					√
Drug distribution		√	√	√	√	√
Drug combination		√	√	√	√	√	√
Adverse event			√	√	√	√	√
Exit criteria assessment			√	√	√	√	√

Note: the urine pregnancy test is screened in fertile women aged from 18 to 50 years

ISSN: 1745-6215