Table 3 Observations and blood sampling

Day

Day 1

Day 1

Day 1

Day 1

Day 2

Day 4

Day 30 (follow-up)

Hours

0 hrs baseline (before infusion)

15 min

2 hrs

6 hrs

24 hrs

72 hrs

Informed consent

X

Demographics/medical history

X

X

X

Weight

X

Clinical parameters^a

X

X

X

X

X

X

Co-medication^b, incl. fluids/blood

X

X

X

X

X

X

Haematology/biochemistry

X

X

X

X

X

X

Thrombelastography

X

X

X

X

X

X

Drug/placebo administration

X

Serious adverse events

X

Mortality

X

X