|
(1) Domains relating to the tinnitus percept:
|
|
Tinnitus loudness
|
70
|
14 %
|
42
|
7 %
|
|
Tinnitus pitch
|
12
|
2 %
|
13
|
2 %
|
|
(2) Domains relating to the impact of tinnitus:
|
|
Tinnitus distress
|
33
|
7 %
|
18
|
3 %
|
|
Tinnitus annoyance
|
22
|
4 %
|
15
|
3 %
|
|
Tinnitus awareness
|
10
|
2 %
|
2
|
0 %
|
|
Cognition
|
2
|
0 %
|
4
|
1 %
|
|
Behaviour
|
1
|
0 %
|
0
|
-
|
|
Acceptance of tinnitus
|
0
|
-
|
3
|
1 %
|
|
Catastrophising
|
0
|
-
|
1
|
0 %
|
|
Concentration
|
0
|
-
|
2
|
0 %
|
|
Tinnitus intrusiveness
|
0
|
-
|
2
|
0 %
|
|
Tinnitus-related cognitions
|
0
|
-
|
1
|
0 %
|
|
Tinnitus-related fear
|
0
|
-
|
1
|
0 %
|
|
(3) Other co-occurring complaints:
|
|
Depression
|
8
|
2 %
|
18
|
3 %
|
|
General distress
|
5
|
1 %
|
5
|
1 %
|
|
Anxiety
|
4
|
1 %
|
6
|
1 %
|
|
Anxiety and depression
|
4
|
1 %
|
13
|
2 %
|
|
Hearing threshold
|
4
|
1 %
|
11
|
2 %
|
|
Hearing loss
|
2
|
0 %
|
1
|
0 %
|
|
Speech perception
|
2
|
0 %
|
0
|
-
|
|
Hearing handicap
|
1
|
0 %
|
3
|
1 %
|
|
Hearing loss annoyance
|
1
|
0 %
|
0
|
-
|
|
Sleep quality
|
1
|
0 %
|
12
|
2 %
|
|
Somatic sensations
|
1
|
0 %
|
1
|
0 %
|
|
Fear (anxiety)
|
0
|
-
|
1
|
0 %
|
|
Hyperacusis
|
0
|
-
|
3
|
1 %
|
|
Mood
|
0
|
-
|
2
|
0 %
|
|
Sound tolerance
|
0
|
-
|
1
|
0 %
|
|
Speech discrimination
|
0
|
-
|
3
|
1 %
|
|
(4) Health-related quality of life (QoL):
|
|
QoL (tinnitus)
|
16
|
3 %
|
13
|
2 %
|
|
QoL
|
9
|
2 %
|
20
|
3 %
|
|
Coping
|
3
|
1 %
|
0
|
-
|
|
Occupational health
|
0
|
-
|
1
|
0 %
|
|
QoL (hearing)
|
0
|
-
|
1
|
0 %
|
|
Sense of control
|
0
|
-
|
1
|
0 %
|
|
(5) Body structures and functions:
|
|
Neck mobility
|
1
|
0 %
|
1
|
0 %
|
|
Neural activity
|
1
|
0 %
|
2
|
0 %
|
|
Oxidative stress
|
1
|
0 %
|
0
|
-
|
|
Active myofascial trigger points
|
0
|
-
|
1
|
0 %
|
|
Blood parameters
|
0
|
-
|
1
|
0 %
|
|
Gene expression
|
0
|
-
|
1
|
0 %
|
|
Metabolism
|
0
|
-
|
4
|
1 %
|
|
Neck pain
|
0
|
-
|
1
|
0 %
|
|
Neuroendocrine hormones
|
0
|
-
|
1
|
0 %
|
|
Pharmacokinetics
|
0
|
-
|
1
|
0 %
|
|
Structural brain change
|
0
|
-
|
1
|
0 %
|
|
(6) Adverse events or harms:
|
|
Safety and tolerability
|
6
|
1 %
|
4
|
1 %
|
|
Safety
|
2
|
0 %
|
43
|
7 %
|
|
Drug safety and tolerability
|
1
|
0 %
|
4
|
1 %
|
|
Side effects
|
1
|
0 %
|
15
|
3 %
|
|
Headache
|
0
|
-
|
1
|
0 %
|
|
Pain frequency
|
0
|
-
|
1
|
0 %
|
|
Pain intensity
|
0
|
-
|
1
|
0 %
|
|
(7) Satisfaction:
|
|
Treatment satisfaction
|
1
|
0 %
|
5
|
1 %
|
|
(8) Treatment-related outcomes:
|
|
Withdrawals
|
1
|
0 %
|
0
|
-
|
|
Adequacy of blinding
|
0
|
-
|
1
|
0 %
|
|
Credibility (sham)
|
0
|
-
|
1
|
0 %
|
|
Credibility (treatment)
|
0
|
-
|
2
|
0 %
|
|
Needling sensation (acupuncture)
|
0
|
-
|
1
|
0 %
|
|
Therapeutic alliance
|
0
|
-
|
1
|
0 %
|
|
Tolerability
|
0
|
-
|
5
|
1 %
|
|
(9) Domain of interest unclear or not specified by the authors:
|
|
Not specified
|
128
|
25 %
|
140
|
24 %
|
|
Cannot code
|
58
|
11 %
|
76
|
13 %
|
|
Multi-domain specification
|
10
|
2 %
|
10
|
2 %
|
|
Tinnitus severity
|
69
|
14 %
|
29
|
5 %
|
|
Tinnitus handicap
|
14
|
3 %
|
5
|
1 %
|
|
Total
|
505
|
100 %
|
579
|
100 %
|
