Table 4 Random intercept models adjusted for fillings, patients, and dentists for all fillings (within and outside the manufacturer’s indications) without 0 year: excluding observations in the first half year (total = 1713 observations)

P value for treatment

0.127

0.123

0.104

0.125

0.125

0.124

0.142

0.194

P value for treatment * time

0.857

1.000

0.996

0.981

1.000

0.827

0.877

0.892

Joint P value for treatment and treatment * time

0.005

0.055

0.070

0.087

0.092

0.122

0.130

0.191

Fixed part: odds ratios

Material Equia (reference: GP fast)

0.63 (0.35–1.14)

0.38 (0.11–1.30)

0.34 (0.09–1.25)

0.36 (0.10–1.32)

0.37 (0.10–1.32)

0.38 (0.11–1.30)

0.40 (0.12–1.36)

0.45 (0.14–1.50)

Material GP fast: time effect

 Reference: 1 year

1

1

1

1

1

1

1

1

 2 years

1.48 (1.25–1.75)

2.05 (1.51–2.78)

2.05 (1.52–2.77)

2.06 (1.52–2.78)

2.04 (1.51–2.76)

2.03 (1.51–2.74)

2.04 (1.51–2.75)

2.04 (1.52–2.75)

 3 years

2.18 (1.56–3.05)

4.21 (2.29–7.74)

4.21 (2.30–7.68)

4.24 (2.32–7.75)

4.18 (2.29–7.62)

4.14 (2.28–7.51)

4.16 (2.29–7.54)

4.18 (2.30–7.58)

 4 years

3.23 (1.96–5.32)

8.63 (3.45–21.5)

8.62 (3.49–21.3)

8.74 (3.54–21.6)

8.54 (3.47–21.0)

8.43 (3.45–20.6)

8.48 (3.47–20.7)

8.53 (3.49–20.9)

Material Equia: time effect

 Reference: 1 year

1

1

1

1

1

1

1

1

 2 years

1.45 (1.24–1.68)

2.05 (1.49–2.82)

2.05 (1.49–2.83)

2.05 (1.49–2.82)

2.04 (1.49–2.76)

2.13 (1.55–2.94)

2.11 (1.53–2.90)

2.10 (1.53–2.89)

 3 years

2.09 (1.55–2.84)

4.21 (2.22–7.97)

4.21 (2.22–8.00)

4.20 (2.21–7.97)

4.18 (2.21–7.91)

4.55 (2.40–8.63)

4.44 (2.35–8.39)

4.43 (2.35–8.33)

 4 years

3.03 (1.92–4.78)

8.63 (3.31–22.5)

8.65 (3.30–22.6)

8.90 (3.29–22.5)

8.54 (3.28–22.2)

9.71 (3.72–25.3)

9.36 (3.61–24.3)

9.31 (3.61–24.0)

Upper jaw (ref: lower jaw)

---

---

---

---

0.91 (0.38–2.15)

---

0.71 (0.32–1.57)

0.69 (0.32–1.50)

Tooth type (reference: 4)

 5

---

---

---

---

5.08 (1.30–19.9)

---

4.52 (1.32–15.5)

4.42 (1.32–14.8)

 6

---

---

---

---

2.43 (0.64–9.26)

---

3.51 (1.01–12.1)

3.11 (0.92–10.6)

 7

---

---

---

---

1.45 (0.38–5.52)

---

5.64 (1.55–20.5)

4.59 (1.30–16.3)

 8

---

---

---

---

1.19 (0.09–15.8)

---

8.85 (0.72–108)

10.9 (0.93–127)

Class (reference: class I)

 II

---

---

---

---

---

42.6 (13.9–131)

60.0 (18.1–199)

51.1 (15.7–167)

 II MOD

---

---

---

---

---

296 (43.5–2013)

318 (46.4–2179)

279 (40.9–1899)

Random part:

Filling: intercept

---

4.64 (3.37–5.93)

2.51 (1.71–3.31)

2.54 (1.73–3.34)

2.53 (1.71–3.34)

2.27 (1.48–3.05)

2.24 (1.45–3.02)

2.18 (1.41–2.94)

Patient: intercept

---

---

3.44 (2.51–4.37)

3.37 (2.44–4.29)

3.29 (2.38–4.21)

2.87 (2.04–3.69)

2.76 (1.94–3.57)

2.31 (1.48–3.14)

Dentist: intercept

---

---

---

---

---

---

---

1.62 (0.92–2.32)