Cerebral
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Pupils
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Reacting to light, dilated (size), dilation difference between eyes
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Seizure
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Involuntary contractions or series of contractions of the voluntary muscles
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Myoclonus
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Short lasting involuntary contractions of one or several muscles
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Myoclonus state
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Continuous myoclonus
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Convulsive state
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Continuous seizures or continuous seizure pattern on EEG
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Circulation
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Hypotension
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Mild: MAP >60 mmHg with one inotropic agent and volume infusion
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Moderate: MAP >60 mmHg with full treatment
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Severe: MAP 50–60 mmHg despite full treatment
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Circulatory failure: MAP <50 mmHg for more than 10 min despite full treatment
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Need for pacing
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Resuscitation
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Arrhythmias
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Mild
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Arrhythmias that do not demand treatment
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Moderate
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Stable haemodynamics (MAP >60 mmHg) with treatment
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Severe
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Pulseless VT/VF or unstable haemodynamics despite treatment
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Gastrointestinal
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Mild
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Aspiration, can partly take enteral nutrition
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Moderate
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Aspiration more than 400 ml, cannot take any enteral nutrition
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Severe
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Ileus, bleeding gastric ulcer, need for explorative laparotomy or others
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Urological
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Continuous or intermittent replacement therapy
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Infectious/inflammatory
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Pneumonia
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New or progressing infiltrations on thoracic X-ray
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Fever (not during hypothermia treatment)
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Leucocytosis
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Purulent tracheobronchial secretion
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SIRSa
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At least 2 of 4 SIRS criteria present
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Sepsis
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Sepsis, SIRS caused by an infection
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Severe sepsis
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Sepsis associated with organ dysfunction
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Septic shock
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Sepsis with hypotensionb
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Bleeding and transfusion
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Bleeding
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Mild: no transfusion needed
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Moderate: up to two RBC units/24 hours.
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Severe: more than two RBC units/24 hours
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Critical bleeding in organs: intracranial, intrathecal, intraocular or pericardial
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Other bleeding: retroperitoneal, thorax or solid organs
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Transfusion
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Number of transfusions
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