Pipelle for Pregnancy (PIP): study protocols for three randomised controlled trials

Table 1 Schedule of procedures and outcome measurements for PIP-IVF

	Pre-study	Day 1 of prior cycle	Day 3 of prior cycle-day 3 of IVF/embryo transfer cycle	Day after procedure	IVF cycle/embryo transfer	About 2 weeks after embryo transfer	About 6 weeks gestation	≥12 weeks gestation	Birth
Eligibility screen	x
Informed consent	x
Randomisation		x
Endometrial scratching (intervention group only)			x
Pain (VAS) (intervention group only)			x
Adverse events (intervention group only)			x	x
Bleeding (intervention group only)				x
IVF cycle characteristics					x
Biochemical pregnancy						x
Clinical pregnancy							x
Ongoing pregnancy								x
Live birth									x

ISSN: 1745-6215