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Table 1 Prebreakfast and predinner insulin titration regimens

From: Comparison of exenatide with biphasic insulin aspart 30 on glucose variability in type 2 diabetes: study protocol for a randomized controlled trial

Fasting and/or predinner SMBG PG value (mmol/L) Adjustment
<5.0 -2 U
5.0 to 7.0 No adjustment
7.1 to 7.7 +2 U
7.8 to 10 +4 U
>10 +6 U
  1. BG, blood glucose; SMGB, self-monitored blood glucose
  2. Glycemic targets for titration: Prebreakfast and predinner PG: 5.0 to 7.0 mmol/L. Prebreakfast dose of biphasic insulin aspart 30 is titrated based on the three mean predinner PG values for the 3 days prior to the visit. Predinner dose of biphasic insulin aspart 30 is titrated based on the three mean fasting PG values for the 3 days prior to the visit. The predinner biphasic insulin aspart 30 titration is not increased if the preceding day’s bedtime SMGB value is 5.6 mmol/L