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Table 1 Dose adjustment plan

From: Comparative effectiveness of antihypertensive treatment for older children with primary hypertension: study protocol for a series of n-of-1 randomized trials

 

Initial dose

Dosing adjustment

Maximum dose

Amlodipine

0.1 mg/kg/dose Qday (max 5 mg/day)

Double dose

10 mg/day

Hydrochlorothiazide

1 mg/kg/dose Qday (max 25 mg/day)

Double dose

50 mg/day or 3 mg/kg/day

Lisinopril

0.1 mg/kg/dose Qday (max 10 mg/day)

Double dose

40 mg/day or 0.6 mg/kg/day

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Trials

ISSN: 1745-6215