From: Quality of outcome reporting in phase II studies in pulmonary tuberculosis
Outcome | Definition | No. studies reporting outcome |
---|---|---|
EBA | Fall or rate of change in log10 CFU/ml sputum | 36 |
CFU count | Mean concentration of viable bacilli | 11 |
AFB | Acid-fast bacilli | 3 |
Culture negativity | Proportion, or time to, culture negativity | 8 |
Culture positivity | Proportion, or time to, culture positivity | 10 |
Smear/culture conversion | Proportion converting, or time to conversion | 9 |
Sterilisation | Proportion or time to sterilisation | 2 |
Other culture outcome | For example, persistence, relapse, time to detection, culture status | 4 |
Adverse events | Â | 5 |
Gaffky code | Â | 1 |
Contamination | Of cultures | 1 |
Mortality | Â | 1 |
Symptom disappearance | Proportion with, or time to symptom disappearance | 1 |