Table 1 Parameter estimates for the three potential designs for the motivating example. A simulation was performed to calculate expected sample size, Type I error and power
From: Generalizing boundaries for triangular designs, and efficacy estimation at extended follow-ups
Estimate | Design 1 | Design 2 | Design 3 |
|---|---|---|---|
| Â | (3 analyses) | (4 analyses) | (7 analyses) |
Maximum sample size | 62 | 62 | 66 |
Expected sample size under H0 | 36 | 31 | 30 |
Expected sample size under H1 | 40 | 40 | 39 |
Type I error | 0.0479 | 0.0482 | 0.0484 |
Power | 0.893 | 0.889 | 0.894 |