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Table 3 Range of sample sizes recalculated using internal pilot data

From: An internal pilot study for a randomized trial aimed at evaluating the effectiveness of iron interventions in children with non-anemic iron deficiency: the OptEC trial

Calculated sample size

α = 5 %; 1-β = 80 %; and S2 = 17.4

Δ = 8

Δ = 7

Δ = 6

Using t-test

150

196

266

 

Multiplication by the design factor (1- ρ2) = 0.21

Using ANCOVA

32

42

56

  1. α significance level, 1-β power, S 2 SD, Δ effect estimate