Efficacy and safety of electroacupuncture with different acupoints for chemotherapy-induced nausea and vomiting: study protocol for a randomized controlled trial

Table 1 The schedule of enrollment, interventions, and assessments

	Study Period
	Enrollment	Allocation	Post-allocation					closeout
Time point	-t1	0	t1	t2	t3	t4	t5	t6
Enrollment:
Eligibility screen	×
Informed consent	×
Allocation		×
Interventions:
Control group
Experimental group I			×	×	×	×
Experimental group II			×	×	×	×
Experimental group III			×	×	×	×
Assessments:
baseline variables	×	×
The frequency of nausea and vomiting		×	×	×	×	×	×	×
The grading of nausea and vomiting		×	×	×	×	×	×	×
Rhodes Index of nausea, vomiting and retching		×	×	×	×	×	×	×
the grading of constipation and diarrhea		×	×	×	×	×		×
electrogastrogram		×					×	×
the assessment of quality of life		×					×	×
the assessment of anxiety and depression		×					×	×
other adverse effect during the chemotherapy							×	×
the adverse effects of acupuncture			×	×	×	×

t1, the day before the chemotherapy; t1-t5, the first day to the fifth day of chemotherapy; t6, the 21st day of chemotherapy.

ISSN: 1745-6215