Week
|
0
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
---|
|
Baseline
|
Treatment period (4 to 8 session)
| | | |
Follow-up
|
---|
Sign informed consent
|
√
| | | | | | | | |
TNSS
|
√
|
√
|
√
|
√
|
√
| | | | |
TNNSS
|
√
|
√
|
√
|
√
|
√
| | | | |
Physical sign
|
√
|
√
|
√
|
√
|
√
| | | | |
RQLQ score
|
√
|
√
|
√
|
√
|
√
| | | | |
IgE level
|
√
| | | |
√
| | | | |
Eosinophil count
|
√
| | | |
√
| | | | |
Number of days with moderate-severe PER in the last month
|
√
| | | | | | | |
√
|
Allergen test
|
√
| | | | | | | | |
Randomization
|
√
| | | | | | | | |
Onset time
| |
√
|
√
|
√
|
√
| | | | |
Duration of effectiveness in every session
| |
√
|
√
|
√
|
√
| | | | |
Waiting time
| |
√
|
√
|
√
|
√
| | | | |
Adverse event
| |
√
|
√
|
√
|
√
| | | | |
- TNSS, Total nasal symptom score; TNNSS, Total non-nasal symptom score; RQLQ, Rhinoconjunctivitis Quality of Life Questionnaire.