| Time 1a: enrollment | Time 2b: baseline assessment | Time 3: intervention | Time 4c: at the end of intervention | Time 5d: 90- day follow-up | |
---|---|---|---|---|---|---|
Informed consent obtained | √ |  |  |  |  | |
Epidemic data collection | √ |  |  |  |  | |
Medical history collection | √ |  |  |  |  | |
Physical examination | √ |  |  |  |  | |
Recruitment criteria assessment | √ |  |  |  |  | |
Randomized allocation |  | √ |  |  |  | |
Physiological data collection | Body temperature |  | √ | √ |  |  |
Respiratory rate |  | √ | √ |  |  | |
Pulse rate |  | √ | √ |  |  | |
Blood pressure |  | √ | √ |  |  | |
Surface electrocardiogram |  | √ | √ |  |  | |
Peripheral blood oxygen saturation |  | √ | √ |  |  | |
Primary outcome measurement (Barthel index) |  | √ |  | √ | √ | |
Secondary outcome measurement | NIHSS score |  | √ |  | √ | √ |
mRS score |  | √ |  | √ | √ | |
3-oz water swallow test |  | √ |  | √ | √ | |
sEMG |  | √ |  | √ | √ | |
Adverse events record |  | √ | √ | √ | √ |