- Paper Report
- Open Access
Diabetic AMI patients receive suboptimal thrombolytic treatment
- Joanna Lyford1
© Biomed Central Ltd 2001
- Received: 19 January 2001
- Published: 19 October 2001
- Diabetes mellitus, mortality, myocardial infarction, retinal hemorrhage, thrombolysis
Danish research published in the December issue of The European Heart Journal reveals that diabetic patients with acute myocardial infarction (AMI) are less likely to be treated with thrombolysis than their non-diabetic counterparts.
Analysis of the data revealed that diabetic AMI patients have a grossly increased long-term mortality, with 7-year mortality rates as high as 79% in insulin-treated, 73% in tablet-treated and 62% in diet-treated diabetic patients, compared with 46% in non-diabetic patients. They also found that even though the diabetic patients had the same frequency of ST-segment elevation and the same admission delay, treatment with thrombolysis and aspirin was significantly less frequently prescribed to diabetic patients than to non-diabetic patients.
The authors evaluated the pre-admission history, presentation, initial treatment and long-term mortality of 6676 patients with AMI who were enrolled into the Trandolapril Cardiac Evaluation (TRACE) study. In this cohort, 719 (11%) of the patients had a history of diabetes.