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Table 1 Intravenous glycoprotein IIb/IIIa antagonists

From: Platelet glycoprotein IIb/IIIa receptor blockade in coronary artery disease

 

Abciximab

Eptifibatide

Tirofiban

Lamifiban

Structure

Antibody Fab fragment

Cyclic heptapeptide

Non-peptide

Non-peptide

Plasma half-life

10–30 min

∼ 2.5 h

∼ 2 h

∼ 2 h

Excretion

Unknown

∼ 50% renal

39–69% renal

90% renal