From: A concept for trial institutions focussing on randomised controlled trials in surgery
Trial/ISRCTN | Interventions | Primary Endpoint | Sample size/Randomised patients/Clinical Sites | |
---|---|---|---|---|
KSC | BEGER/BERN 50638764 [17] | Beger vs Berne procedure for surgical treatment of chronic pancreatitis | Duration of surgery Quality of life Time at ICU Duration of hospital stay | 65/65 |
POUCH 78983587 | Transverse Coloplasty versus J-Pouch for low anterior rectal resection | Difficulties with evacuation after 2 years | 150/150 | |
POVATI 60734227 [18] | Midline vs transverse laparotomy | Pain and use of analgesics | 200/200 | |
LAPCON-POUCH 61411448 [19] | Laparoscopic vs. open total proctocolectomy with ileo-anal pouch anastomosis | Blood loss Units packed cells | 130/30 | |
PORTAS 52368201 [20] | Venae Sectio vs. modified Seldinger Technique for Totally Implantable Access Ports | Primary success rate of surgical technique | 164/164 | |
SDGC | INSECT 24023541 [14] | Running vs interrupted fascia closure after midline laparotomy | Incisional hernia | 600/624/25 |
CLIVIT 96901396 [15] | Clips vs ligation in thyroid surgery | Duration of surgery | 400/265/5 | |
DISPACT 18452029 | Stapling vs scalpel transsection and hand-suture for distal pancreatectomy | Pancreatic fistula and mortality | 550/101/25 | |
TOPAR-PILOT 86202793 [21] | Autotransplantation vs none after total parathyroidectomy | Recurrence of secondary hyperparathyroidism | 100/16/7 |