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Figure 5 | Trials

Figure 5

From: Comparison of anticipated and actual control group outcomes in randomised trials in paediatric oncology provides evidence that historically controlled studies are biased in favour of the novel treatment

Figure 5

Relative differences for historical control comparison and randomised comparison. Solid dots, triangles or squares represent the hazard ratios (HRs) or risk ratios (RRs) for a randomised comparison. The crosses represent the HRs or RRs for the historical control comparison (HCC). The solid vertical lines show the median HRs or RRs for the randomised comparison. The dashed vertical lines show the median HRs or RRs for the HCC. For example, for the 48th question, the HR for the randomised comparison is 1.66, whereas it is 2.29 for the HCC.

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Trials

ISSN: 1745-6215