Inclusion criteria | Exclusion criteria |
---|---|
(1) Diagnosis of primary glomerulonephritis | (1) Secondary nephropathy |
(2) Aged 18 to 70Â years | (2) Taken glucocorticoid, immunosuppressants or Tripterygium drugs in the last 12Â months |
(3) Blood pressure ≤140/90 mmHg | (3) Therapy with other Chinese patent medicines or decoctions that can reduce proteinuria in the last 2 weeks |
(4) Estimated glomerular filtration rate ≥45 mL/min/1.73 m2 | (4) Therapy with renin-angiotensin system blockers in the last 4 weeks |
(5) 24-hour proteinuria level 0.5 to 3.0 g | (5) Severe primary disease of the heart, brain, liver, or hematopoietic system, or other serious diseases that can affect the patient’s life |
(6) Traditional Chinese medicine syndrome conforming to Qi-Yin deficiency | (6) Pregnancy or lactation |
(7) Agreement to participate by the patient or their guardians with written informed consent | (7) Allergic predisposition or known allergy to the drug composition |
 | (8) Blood pressure <90/60 mmHg |
 | (9) Unilateral or bilateral renal artery stenosis |
 | (10) Mental disorders and poor compliance |
 | (11) Suspected or confirmed history of alcohol or drug abuse |
 | (12) Participation in another clinical study at the same period |