Funnel plot of 1/SE(log(OR)) versus OR for ICH in Phase II and Phase III trials. Dotted line represents the summary treatment effect estimate for ICH from the Bayesian random-effects logistic regression analysis (model 2) of the Phase II trials; dashed line indicates the summary treatment effect estimate for ICH by Eikelboom et al.  for the Phase III trials. The OR axis is shown on the log-scale. OR odds ratio; ICH intracranial hemorrhage, SE standard error.