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Figure 3 | Trials

Figure 3

From: Meta-analysis of randomized phase II trials to inform subsequent phase III decisions

Figure 3

Comparison of Bayesian prediction interval from Phase II meta-analysis with original meta-analysis and subsequent Phase III trials for ICH. lnTIME-II, ASSENT-2, BIRD, GUSTO-III, COBALT and INJECT are the six subsequent Phase III trials, which compared bolus to infusion therapy for patients with an acute myocardial infarction. Horizontal lines indicate the 95% confidence intervals for the estimated log ORs in the Phase III trials and the original Phase II meta-analysis, and the 95% prediction interval in the Bayesian Phase II meta-analysis [2227].

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