Efficacy of lidocaine in patients receiving palliative care with opioid-refractory cancer pain with a neuropathic component: study protocol for a randomized controlled study

Table 3 Study procedure

	T0	T1, T2, T3	T4, T5	T6
	Inclusion	Administration	Post-administration	Day-14
Consent	x
Randomization	x
Clinical examination	x
NPIS	x	x	x	x
NPSI	x	x	x	x
ECG	x	x
Tolerance		x
Opioid consumption		x	x	x
MDASI	x		x
Adverse events		x	x	x
Intercurrent events		x	x	x
Satisfaction PTSS	x		x	x

ECG, electrocardiograph; MDASI, MD Anderson Symptom Inventory; NPIS, Numeric Pain Intensity Scale; NPSI, Neuropathic Pain Symptom Inventory; PTSS, Pain Treatment Satisfaction Scale.

ISSN: 1745-6215