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Table 2 Time-dependent quantitative results for the GOG111 trial

From: An approach to trial design and analysis in the era of non-proportional hazards of the treatment effect

Quantity t=2 yr t=5 yr
  Est. 95% CI Est. 95% CI
HR (t) 0.71 (0.57,0.89) 0.99 (0.71,1.39)
S 0(t) 0.52 (0.46,0.58) 0.18 (0.13,0.23)
S 1(t) 0.68 (0.62,0.73) 0.27 (0.22,0.33)
S 1(t)-S 0(t) 0.16 (0.07,0.24) 0.09 (0.02,0.16)
RMST 0 (yr) 1.53 (1.45,1.61) 2.44 (2.22,2.67)
RMST 1 (yr) 1.73 (1.66,1.79) 3.04 (2.81,3.26)
RMST 1- RMST 0 0.20 (0.09,0.30) 0.59 (0.27,0.91)
  1. Note that the estimated hazard ratio, HR(t), is instantaneous. See text for further details.